On June 5, 2021 Dr. Maria Delfina Molinaro passed away in her home of Pavia. After the master degree in Biological Sciences in 1987, Dr. Delfina Molinaro started attending the Department of Pharmacology at San Matteo Hospital in Pavia, at that time directed by prof. Renato Rondanelli, one of the founding fathers of Pharmacology in Italy. Subsequently, Dr. Delfina Molinaro joined the Therapeutic Monitoring Lab lead by Dr. Mario Regazzi who, over the course of time, became her teacher and mentor. In over thirty years spent at San Matteo, Dr. Delfina Molinaro has been mainly involved in both research activities and clinical diagnostics in the therapeutic drug monitoring of anti-infectious and immunosuppressive drugs, with dozens of scientific publications in the fields.
I personally met Delfina twenty years ago during an IATDMCT congress and immediately an affinity was born which then became a solid friendship. Our “fights” were proverbial, being both very stubborn and bloodthirsty, because this was our way of discussing. But at the end of each quarrel our friendship came out more and more strengthened …
Only a few months ago, immediately before the dramatic discovery of her disease, Delfina was interviewed by Jana Stojanova for the IATDMCT Blog. When Jana asked her “What sort of research do you have on the horizon that you think might influence clinical practice in the future?”, The reply of Delfina was “I feel lucky to be part of an enthusiastic group of professionals who have also become very close friends over time and who have proved to be a source of ideas about methods to improve patients’ care. We have already come a long way, but I am sure that many improvements can still be made to truly personalize therapy, keeping in mind that more and more often we deal with combination therapies including immunosuppressive drugs, antimicrobials, antifungals, antivirals, and so on”.
Let us, therefore, honor Dr Molinaro’s memory by remembering that patients are not averages but individuals. Each patient deserves pharmacologic therapies with optimized, tailored dosing. For this reason, the members of the local organizing committee of the Rome IATDMCT 2021 Meeting unanimously decided to establish the “Maria Delfina Molinaro Award” for the best work presented at the congress in the field of personalization of therapy.
Rest in peace my dear friend